refractory phase

基本解释

Severe hepatotoxic events are also noted for an ongoing phase 1/2 combination study in pediatric patients with relapsed or refractory acute leukemia.
一项处于开展阶段的在难治性或复发性急性白血病儿童患者中进行的合并用药1/2期研究中，也发现严重的肝毒性事件。
We report the results of a phase II, single-arm, multicenter trial evaluating the safety and efficacy of lenalidomide oral monotherapy in patients with relapsed or refractory aggressive NHL.
我们在此报道一个II期多中心单一研究项试验，以评价来那度胺口服单一疗法治疗复发性或难治性侵袭性NHL的安全性和有效性。
A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia.
替匹法尼用一周，停一周剂量递增治疗复发性，难治性或高危髓细胞性白血病1阶段试验。